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26-27 Nov 2019
Frankfurt
 The Targeting RNA congress will discuss the latest advancements in modulation of RNA (splicing/non-coding/micro) directly with small molecules and through epigenetics. The meeting will showcase structures of small molecules binding to disease relevant RNA and innovations in building hit-to-lead RNA specific platforms both essential for proof-of concept.Bringing together leaders in academics and industry such as Novartis, Merck, Gotham Therapeutics and University of Cambridge, who are building platforms to identify and validate targets, in order to assess in disease relevance approaches in the relatively untapped RNA world. The meeting will also discuss translational strategies, addressing structural biology, biochemical and biophysical attributes, chemical hurdles associated with new drug discovery platforms.What to expect:Opportunities to engage with key players from biotech, pharma, and academia that are building platforms to target RNA with small molecules, modify the RNA with enzymes (epigenetics) and indirectly through protein-RNA interactions.Hear how to overcome 2D structural biology parameters from leading European RNA biologists and computational biologists and emerging European epigenetics companies.The first European translational event focusing on modifying RNA upstream regulation to enable preventive medicine instead of treating symptoms with small molecules and epitranscriptomics.A meeting bridging the gap between the key research challenges such as target identification (chemo-proteomics, 2D/3D structures) and validation (small molecule binding efficiencies, selectivity and stability) and sharing new methodologies and process for obtaining hit to lead products in the RNA space.
 

Adam Lisberg

Corporate Communications Director
DJI

Adam Lisberg

Corporate Communications Director
DJI

Adam Lisberg

Corporate Communications Director
DJI
 

Douglas Moule

Operations Manager
easyJet

Douglas Moule

Operations Manager
easyJet

Douglas Moule

Operations Manager
easyJet
 

Brendan Booth

Safety Manager
easyJet

Brendan Booth

Safety Manager
easyJet

Brendan Booth

Safety Manager
easyJet
Millie Kendall on the Beauty Industry
 
WOMEN IN TARGETING THE UNDRUGGED
16-24 Feb 2021
VIRTUAL CONGRESS | EST TIMEZONE
The targeted protein degradation field is expanding, gone are the days of simple proof of concept…. We now have LYTACs, AUTACs and ATTECs as well as numerous PROTAC and Molecular Glue companies with millions of dollars worth of investment. C4 netted $182.4 million in IPO, and Nurix and Kymera closed funding with $120 million and $102 million apiece. With several start-ups launching, including Lycia and Amphista therapeutics, investment in this area is booming, and it’s not slowing down.There are currently over 85 degraders being considered at various stages of development, both preclinical and clinical, as well as in discovery. However, key questions are yet to be answered:How will degrader research translate in the clinic?Why are we still struggling with oral bioavailability?How can we effectively validate novel targets and degrade ‘undruggable’ targets of interest?What can be learned from the new, emerging degrader strategies that are emerging?Once again bringing together leaders from pharma, biotech and academia as well as innovative service providers, the North American Protein Degradation Congress is back to give you the full picture from molecular biology right the way up to the latest in medicinal chemistry and clinical data.Learn to create clinically applicable degraders to the entire proteome at the digital North American Protein Degradation Congress 2021.
Habana - Gaudi Training Platform
 

Paras Koushal

Drug Safety Physician
Accenture

Paras Koushal

Drug Safety Physician
Accenture

Paras Koushal

Drug Safety Physician
Accenture
 

Mikihiko Naito

Chief, Division of Molecular Target and Gene Therapy Products
National Institute of Health Sciences

I have been studying cancer chemotherapy, cell death and protein degradation for many years, and developed SNIPER technology for targeted protein degradation. A goal of my research is to develop a novel drug based on the SNIPER technology. I have been collaborating with many researchers, and currently trying to start a new research group to accelerate the drug development.

Mikihiko Naito

Chief, Division of Molecular Target and Gene Therapy Products
National Institute of Health Sciences

Mikihiko Naito

Chief, Division of Molecular Target and Gene Therapy Products
National Institute of Health Sciences

I have been studying cancer chemotherapy, cell death and protein degradation for many years, and developed SNIPER technology for targeted protein degradation. A goal of my research is to develop a novel drug based on the SNIPER technology. I have been collaborating with many researchers, and currently trying to start a new research group to accelerate the drug development.

I love to eat chocolate with a cup of hot delicious tea. However, this combination facilitates producing kidney stones, which sometimes gave me painful experiences. I wish I could have them everyday without any concerns on the kidney stones.