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Julien Muller

CEO
Holidog

Julien Muller

CEO
Holidog

Julien Muller

CEO
Holidog
 

Mariot Chauvin

Head of Engineering
The Guardian

Mariot Chauvin

Head of Engineering
The Guardian

Mariot Chauvin

Head of Engineering
The Guardian
 

Russell Warman

Head of Infrastructure
Auto Trader UK

Russell Warman is Head of Infrastructure and Operations at Auto Trader, the UK's largest digital automotive marketplace

He leads the team charged with the capacity and performance of one the UK’s busiest websites - autotrader.co.uk, which sits at the heart of the UK's vehicle buying process. The team have a cloud native approach to enable our developers to make more frequent changes safely and are increasingly looking at public cloud services to help achieve that aim.

Russell Warman

Head of Infrastructure
Auto Trader UK

Russell Warman

Head of Infrastructure
Auto Trader UK

Russell Warman is Head of Infrastructure and Operations at Auto Trader, the UK's largest digital automotive marketplace

He leads the team charged with the capacity and performance of one the UK’s busiest websites - autotrader.co.uk, which sits at the heart of the UK's vehicle buying process. The team have a cloud native approach to enable our developers to make more frequent changes safely and are increasingly looking at public cloud services to help achieve that aim.

Best in Show Finalists 2020
 
European Protein Degradation Congress
22-23 May 2019
Basel, Switzerland
“Targeted protein degradation promises to be the greatest innovation in small molecule drug discovery in the new millennium.” - Manfred Koegl, Lab Head Oncology Research, Boehringer IngelheimWith capital investment coming in fast, industry is ready to commercialise the therapeutic potential of PROTACs and molecular glues to build safe, effective targeted protein degradation products. As Arvinas conducts the groundbreaking first PROTAC clinical trials this year, it could be only be a matter of time before PROTACs and molecular glues enter the market. The European Protein Degradation Congress will bring together leading industry players within big pharma and biotech along with expert academics in the ubiquitin space - providing an open forum and facilitate the sharing of in vitro and in vivo data, as well as build a deeper mechanistic understanding of the ubiquitin pathways and techniques to make the ‘undruggable’ druggable.Expect to hear strategies to overcome the structural biology, pharmacology and chemistry obstacles associated with the discovery and development of these bi-functional and single entity molecules.
 

Gwenn Hansen

Vice President of Drug Discovery Technologies
Nurix Therapeutics

Gwenn is Vice President of Drug Discovery Technologies at Nurix Therapeutics, a company focused on discovering and developing next-generation therapies that target protein homeostasis through modulation of the ubiquitin proteasome system. Since joining Nurix in January of 2016, Gwenn has focused on establishing the company’s DNA encoded library technology platform for small molecule discovery, and now leads teams of scientists in both early discovery as well as medicinal chemistry.

Gwenn Hansen

Vice President of Drug Discovery Technologies
Nurix Therapeutics

Gwenn Hansen

Vice President of Drug Discovery Technologies
Nurix Therapeutics

Gwenn is Vice President of Drug Discovery Technologies at Nurix Therapeutics, a company focused on discovering and developing next-generation therapies that target protein homeostasis through modulation of the ubiquitin proteasome system. Since joining Nurix in January of 2016, Gwenn has focused on establishing the company’s DNA encoded library technology platform for small molecule discovery, and now leads teams of scientists in both early discovery as well as medicinal chemistry. Prior to joining Nurix, Gwenn spent one year as an Associate Professor in the Center for Drug Discovery at Baylor College of Medicine and over 13 years in a variety of discovery-focused roles at Lexicon Pharmaceuticals, both located in Houston, Texas.  Gwenn received her PhD in Biomedical Sciences from Oak Ridge National Laboratory in 1998 and completed postdoctoral training at MD Anderson Cancer Center. 

 

Kirti Sharma

Director, Proteomics
Kymera Therapeutics

Kirti Sharma

Director, Proteomics
Kymera Therapeutics

Kirti Sharma

Director, Proteomics
Kymera Therapeutics
 

Sara Buhrlage

Assistant Professor of Biological Chemistry and Molecular Pharmacology
Dana Farber Cancer Institute

Sara Buhrlage, PhD, is an Assistant Professor in Dana-Farber’s Cancer Biology Department and Harvard Medical School’s Biological Chemistry and Molecular Pharmacology Department. Her research group focuses on the development of first-in-class inhibitors and prototype drugs for deubiquitylating enzymes (DUBs) that can be utilized to pharmacologically validate members of the gene family as new targets for cancer treatment and other diseases.

Sara Buhrlage

Assistant Professor of Biological Chemistry and Molecular Pharmacology
Dana Farber Cancer Institute

Sara Buhrlage

Assistant Professor of Biological Chemistry and Molecular Pharmacology
Dana Farber Cancer Institute

Sara Buhrlage, PhD, is an Assistant Professor in Dana-Farber’s Cancer Biology Department and Harvard Medical School’s Biological Chemistry and Molecular Pharmacology Department. Her research group focuses on the development of first-in-class inhibitors and prototype drugs for deubiquitylating enzymes (DUBs) that can be utilized to pharmacologically validate members of the gene family as new targets for cancer treatment and other diseases. DUBs have garnered significant attention recently as potential therapeutic targets in the field of oncology due to their removal of degradative ubiquitin marks from cancer causing proteins.

Prior to joining as a faculty member in July 2015, Dr. Buhrlage was a professional track scientist at Dana-Farber in the medicinal chemistry core laboratory. In this role she collaborated with Institute researchers to pharmacologically validate novel targets of disease and study mechanisms of oncogenesis and drug resistance.

Dr. Buhrlage completed a Doctor of Philosophy in organic chemistry in 2008, under the direction of Professor Anna Mapp, PhD, from the University of Michigan, where she successfully designed, synthesized and characterized small molecules that bind the transcriptional co-activator CBP and upregulate transcription when tethered to DNA. Following completion of her Doctor of Philosophy, Dr. Buhrlage trained for two years in medicinal chemistry at the Broad Institute.